Cellular characterization of the peritumoral brain zone of glioblastomas: heterogenous nature and clinical relevance.
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez-González, Beatriz Herranz-Sanchez, Alicia Avis-Bodas, Ana Ramos, Juan Manuel Sepúlveda-Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, P. González, Luis Jimenez Roldan, Guillermo García-Posadas, Aurelio Hernández‐Laín, , Pilar Sánchez‐Gómez
This study characterizes the heterogeneity of the GBM periphery, showing that non-enhancing areas have neoplastic features and that tumor infiltration correlates with patient sex, age, and resection extent, impacting prognosis.
bioRxiv · Mar 9, 2025 · PreprintCancer Biology