Constructing genotype and phenotype network helps reveal disease heritability and phenome-wide association studies
Xuewei Cao, Lirong Zhu, Xiaoyu Liang, Shuanglin Zhang, Qiuying Sha
This study constructs a bipartite Genotype and Phenotype Network to analyze genetic associations and improve phenome-wide association studies by identifying pleiotropic loci and controlling false discovery rates.
BMC Genomics · Dec 12, 2025Peer-reviewedGenetic & Genomic Medicine