GenomicsFrontiers in GeneticsPeer-reviewed
Empirical Bayes estimation of semi-parametric hierarchical mixture models for unbiased characterization of polygenic disease architectures
Jo Nishino, Yuta Kochi, Daichi Shigemizu…·Shigeyuki Matsui
The paper uses empirical Bayes estimation of semi-parametric hierarchical mixture models to analyze GWAS summary statistics and characterize the polygenic architectures of schizophrenia and rheumatoid arthritis.
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