Persistence of a SARS-CoV-2 variant with a frameshifting deletion for the duration of a major outbreak
Charles S. P. Foster, Rowena Anne Bull, Nicodemus T. Tedla, Fernando S. Santiago, David Agapiou, Anurag Adhikari, Gregory J. Walker, Lok Bahadur Shrestha, Sebastiaan J. van Hal, Ki Wook Kim, William D. Rawlinson
The paper identifies a SARS-CoV-2 variant with an ORF7a deletion that persisted during a major outbreak but shows no clear fitness advantage in cell culture.
medRxiv · Sep 6, 2022 · PreprintGenetic & Genomic Medicine