Author

Dante S. LAURETTA

University of ArizonaORCID 0000-0002-2597-5950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Assay:protein sequence· 1

Frequent Co-Authors

Andrew L. WheeleriD· 2 shared Bùi Quang MinhiD· 2 shared Joanna MaseliD· 2 shared Sawsan WehbiiD· 2 shared Benoit MoreliD· 1 shared Nandini ManepalliiD· 1 shared Nhan Ly-TrongiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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7 top collaborators · 19 mutual co-author links

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2 shared papersEvolutionary Biology

Andrew L. WheelerORCID

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2 papers

Recent·Most cited

Tryptophan became part of the universal genetic code post-LUCA

Sawsan Wehbi, Nhan Ly-Trong, Andrew L. Wheeler, Bùi Quang Minh, Dante S. LAURETTA, Joanna Masel

The paper investigates whether tryptophan was present in LUCA by analyzing the evolution of tryptophanyl-tRNA synthetase and finds that W usage originated in Bacteria with later horizontal transfer to Archaea.

bioRxiv · Jun 20, 2026 · PreprintEvolutionary Biology

Order of amino acid recruitment into the genetic code resolved by Last Universal Common Ancestor's protein domains

Sawsan Wehbi, Andrew L. Wheeler, Benoit Morel, Nandini Manepalli, Bùi Quang Minh, Dante S. LAURETTA, Joanna Masel

The paper infers the order of amino acid recruitment into the genetic code by analyzing ancestral protein domain frequencies, finding smaller amino acids were added earlier and metal-binding/sulfur-containing amino acids earlier than previously thought.

Proceedings of the National Academy of Sciences · Dec 12, 2024Peer-reviewedEvolutionary Biology