Denoising Single-Cell RNA-Seq Data with a Deep Learning-Embedded Statistical Framework
Qinhuan Luo, Yongzhen Yu, Tianying Wang
ZILLNB denoises and imputes scRNA-seq data by combining zero-inflated negative binomial regression with deep generative modeling, improving gene expression accuracy and subpopulation identification.
BMC Bioinformatics · Nov 19, 2025Peer-reviewedBioinformatics