Okan Bilge Özdemir

G2DBridge: A Multimodal Framework Linking Genetics to Disease through Imaging Intermediates

G2DBridge links genetic variation to disease risk by modeling imaging-derived phenotypes as intermediate traits, improving Alzheimer's Disease prediction over polygenic risk scores without new data.

A Deep Ensemble Encoder Network Method for Improved Polygenic Risk Score Prediction

This paper introduces DEEN, a deep learning method that improves polygenic risk score prediction by modeling both linear and non-linear SNP effects, showing better performance on UK Biobank and All of Us datasets.