ComBat Harmonization: Empirical Bayes versus Fully Bayes Approaches
Maxwell J. Reynolds, Tigmanshu Chaudhary, Mahbaneh Eshaghzadeh Torbati, Dana Tudorascu, Kayhan N. Batmanghelich, the Alzheimer’s Disease Neuroimaging Initiative
This paper compares empirical Bayes and fully Bayesian approaches for harmonizing neuroimaging data, finding empirical Bayes more efficient but underestimating uncertainty, while fully Bayesian better preserves biological information.
NeuroImage Clinical · Jan 1, 2023Peer-reviewedNeuroscience