Quantification of biases in predictions of protein stability changes upon mutations
Fabrizio Pucci, Katrien V. Bernaerts, Jean Marc Kwasigroch, Marianne J. Rooman
The paper analyzes biases in protein stability prediction tools and proposes a symmetry-based solution to reduce bias towards destabilizing mutations.
Bioinformatics · Apr 25, 2018Peer-reviewedBioinformatics