Ground-truth in silico spike-ins reveal limits of microbiome biomarker recovery in colorectal cancer
André Salgado, Catarina Rosa Tomaz, Ana T. Freitas, Ana Santos Almeida
This study evaluates the recovery of CRC-associated microbiome biomarkers using in silico spike-ins, revealing limitations in detection and quantification across different profiling workflows.
bioRxiv · Aug 6, 2026 · PreprintBioinformatics