Harnessing Expressed Single Nucleotide Variation and Single Cell RNA Sequencing to Define Immune Cell Chimerism in the Rejecting Kidney Transplant
Andrew F. Malone, Hao Wu, Catrina C. Fronick, Robert S. Fulton, Joseph P. Gaut, Benjamin D. Humphreys
The paper uses exome sequencing and scRNA-seq to identify donor and recipient immune cells in kidney transplants and finds distinct transcriptional profiles in donor macrophages and T cells.
Journal of the American Society of Nephrology · Jul 15, 2020Peer-reviewedGenomics