SMURF: embedding single-cell RNA-seq data with matrix factorization preserving selfconsistency
Bingchen Wang, Juhua Pu, Lingxi Chen, Shuai Cheng Li
SMURF embeds scRNA-seq data using matrix factorization with a Poisson-Gamma divergence objective, preserving self-consistency and recovering gene expression and cell cycle time courses.
bioRxiv · Apr 22, 2022 · PreprintBioinformatics