Author

Maria J. Soto

Lawrence Berkeley National LaboratoryORCID 0000-0002-3192-4578Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:metabolomics· 1

Frequent Co-Authors

Byung-Jun YooniD· 2 shared Edward R. Dougherty· 2 shared Francis J. AlexanderiD· 2 shared Ian K. BlabyiD· 2 shared Puhua NiuiD· 2 shared Xiaoning QianiD· 2 shared Shuai HuangiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Byung-Jun YoonORCID

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2 papers

Recent·Most cited

Sensitivity analysis of genome-scale metabolic flux prediction

Puhua Niu, Maria J. Soto, Shuai Huang, Byung-Jun Yoon, Edward R. Dougherty, Francis J. Alexander, Ian K. Blaby, Xiaoning Qian

The paper develops a sensitivity analysis strategy for genome-scale metabolic flux prediction using TRIMER, showing its utility in guiding optimal experimental design for metabolic engineering.

Journal of Computational Biology · Mar 24, 2023Peer-reviewedBioinformatics

TRIMER: Transcription Regulation Integrated with MEtabolic Regulation

Puhua Niu, Maria J. Soto, Byung-Jun Yoon, Edward R. Dougherty, Francis J. Alexander, Ian K. Blaby, Xiaoning Qian

TRIMER integrates transcriptional and metabolic regulation to predict metabolic fluxes and gene states, outperforming existing methods on simulated and experimental data.

iScience · Oct 7, 2021Peer-reviewedBioinformatics