Distinct cerebrospinal fluid DNA methylation signatures linked to Alzheimer's disease
Magdalena Radoš, Sigrid Klotz, Günther Regelsberger, Elisabeth Stögmann, Lukas David Landegger, Irfete Sh. Fetahu
The paper validates DNA methylation signatures for Alzheimer's disease in cerebrospinal fluid-derived cell-free DNA, showing 6 out of 11 signatures are consistent with previous findings in brain tissue.
bioRxiv · Apr 3, 2025 · PreprintNeuroscience