Author

Sánchez-Castañeda Jean Paul

National Institute of Genomic MedicineORCID 0000-0002-3247-7167Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

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Research Focus:benchmarking· 1 Approach:diffusion model· 1 Research Focus:dimensionality reduction· 1 Research Focus:imputation· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Aarón Vázquez-JiméneziD· 1 shared Cristian Padrón-ManriqueiD· 1 shared Daniel Neri-RosarioiD· 1 shared David Giron-VillalobosiD· 1 shared Diego Armando Esquivel-HernandeziD· 1 shared Osbaldo Reséndis-AntonioiD· 1 shared Yoscelina Estrella Martínez-LópeziD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Aarón Vázquez-JiménezORCID

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1 paper

Recent·Most cited

Diffusion on PCA-UMAP manifold captures a well-balance of local, global, and continuum structures to denoise single-cell RNA sequencing data

Cristian Padrón-Manrique, Aarón Vázquez-Jiménez, Diego Armando Esquivel-Hernandez, Yoscelina Estrella Martínez-López, Daniel Neri-Rosario, Sánchez-Castañeda Jean Paul, David Giron-Villalobos, Osbaldo Reséndis-Antonio

The paper introduces sc-PHENIX, an imputation method for scRNA-seq data that addresses over-smoothing issues in diffusion-based approaches by using PCA-UMAP initialization.

bioRxiv · Jun 9, 2022 · PreprintBioinformatics