The WIPI homolog Atg18 binds to and tethers membranes containing phosphatidylinositol-3,4,5-triphosphate.
Fernando L. Noguera-Cañas, Aitor Díaz-Agustín, Jose A. Gavira, José M. Paredes, Rafael Salto, Ángel Orte, Francisco Conejero‐Lara, Mercedes Martín‐Martinez, Ángel Pérez-Lara
This study investigates how Atg18 binds to phosphatidylinositol-3,4,5-triphosphate, showing it clusters membranes and tethers opposing membranes.
bioRxiv · Jan 31, 2025 · PreprintBiophysics