Author

Toby J Curless

National Hospital for Neurology and NeurosurgeryORCID 0000-0002-3277-7813Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Aine Fairbrother-BrowneiD· 2 shared Amy R. HicksiD· 2 shared Emil Karl GustavssoniD· 2 shared Hannah L. MacphersoniD· 2 shared Henry HouldeniD· 2 shared John HardyiD· 2 shared Jonathan BrentoniD· 2 shared Kylie MontgomeryiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Aine Fairbrother-BrowneORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 4, 2025

Molecular and cellular signatures differentiate Parkinson's disease from Parkinson's disease with dementia

Aine Fairbrother-Browne, Melissa Grant‐Peters, Jonathan Brenton…·Mina Ryten

This study compares molecular and cellular signatures of Parkinson's disease and Parkinson's disease with dementia using single-nuclear transcriptomics, finding distinct gene expression patterns and biological pathways.

4 citations

humanscRNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 3, 2025

Transcriptomic analysis of repeat expansion-ataxias uncovers distinct non-neuronal cell type-specific signatures of disease across the human brain

Zhongbo Chen, Amy R. Hicks, Jonathan Brenton…·Mina Ryten

This study uses bulk and single nuclear RNA-sequencing to analyze transcriptomic changes in repeat expansion ataxias, revealing distinct non-neuronal cell type-specific disease signatures across the human brain.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky