Predictive value of preclinical models for CAR-T cell therapy clinical trials: a systematic review and meta-analysis
David Andreu-Sanz, Lisa Gregor, Emanuele Carlini, Daniele Scarcella, Carsten Marr, Sebastian Kobold
This study reviews and meta-analyzes CAR-T cell therapy trials and preclinical models to assess their predictive value, finding that preclinical models poorly predict outcomes when using their own features.
Journal for ImmunoTherapy of Cancer · Jun 1, 2025Peer-reviewedCancer Biology