Deciphering causal relationships between cell type-specific genetic factors and brain imaging-derived phenotypes and disorders
Anyi Yang, Xingzhong Zhao, Yucheng Yang, Xing-Ming Zhao
This study uses Mendelian randomization to identify cell type-specific causal genes linking brain imaging phenotypes and disorders, revealing high specificity and potential therapeutic targets.
medRxiv · Aug 30, 2024 · PreprintGenetic & Genomic Medicine