Structural architecture of amyloid-β oligomers, curvilinear protofibrils and annular assemblies, imaged by cryo-EM and cryo-ET
Ruina Liang, Anum Khursheed, Islam Bogachan Tahirbegi, Andrea P. Torres‐Flores, Shang Qi, Yao Tian, Hui Zhang, Piotr Szwedziak, Vladimir A. Volkov, Vidya C. Darbari, John H. Viles
The paper uses cryo-EM and cryo-ET to characterize the structural architecture of Aβ oligomers, curvilinear protofibrils, and annular assemblies, revealing their structural relationships and functional properties.
Science Advances · Aug 27, 2025Peer-reviewedBiophysics