Author

Dean A. Fergusson

Ottawa Hospital Research InstituteORCID 0000-0002-3389-2485Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Manoj Mathew LaluiD· 2 shared Ahmed Sadeknury· 1 shared Amir Ebrahimi· 1 shared Arvind Singh MeriD· 1 shared Ayni SharifiD· 1 shared Dale CorbettiD· 1 shared Dar D DowlatshahiiD· 1 shared Duncan John StewartiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Manoj Mathew LaluORCID

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2 papers

Recent·Most cited

Artificial Intelligence-enabled Histological Analysis in Preclinical Respiratory Disease Models: A Scoping Review

Eva Kuhar, Junsoo Park, Forough Jahandideh, Majid Komeili, Ahmed Sadeknury, Navneet Kang, Prarthna Karunamurthy, Mohammad Reza Zarei, Amir Ebrahimi, Sean E. Gill, Patricia C. Liaw, Dean A. Fergusson, Duncan John Stewart, Arvind Singh Mer, Manoj Mathew Lalu

This paper reviews AI applications in histological analysis of preclinical respiratory disease models, finding high performance but gaps in validation, transparency, and standardization.

European Respiratory Review · Apr 1, 2026Peer-reviewedCell Biology

Preclinical systematic review of CCR5 antagonists as cerebroprotective and stroke recovery enhancing agents

Ayni Sharif, Matthew Strider Jeffers, Dean A. Fergusson, Raj Bapuji, Stuart Gordon Nicholls, John Humphrey, Warren Johnston, Ed Mitchell, Mary-Ann Speirs, Laura Stronghill, Michele Vuckovic, Susan Wulf, Risa Shorr, Dar D Dowlatshahi, Dale Corbett, Manoj Mathew Lalu

This study reviews preclinical evidence on CCR5 antagonists' effects on stroke outcomes and recovery, finding reduced infarct volume and improved behavioral outcomes, but highlighting significant bias and knowledge gaps.

eLife · Apr 7, 2025Peer-reviewedNeuroscience