Reconstructing tumor evolutionary histories and clone trees in polynomial-time with SubMARine
Linda K. Sundermann, Jeff A. Wintersinger, Gunnar Rätsch, Jens Stoye, Quaid Morris
This paper introduces SubMARine, a polynomial-time algorithm for reconstructing tumor clone trees that efficiently captures uncertainty and scales to large datasets.
PLoS Computational Biology · Jan 19, 2021Peer-reviewedBioinformatics