Generative prediction of causal gene sets responsible for complex traits
Benjamin Kuznets-Speck, Buduka K. Ogonor, Thomas P. Wytock, Adilson E. Motter
The paper develops TWAVE, a generative model that identifies causal gene sets for complex traits by integrating transcriptomic data and gene perturbation responses.
Proceedings of the National Academy of Sciences · Jun 12, 2025Peer-reviewedBioinformatics