Arylsulfonamide mediated RBM39 degradation causes aberrant splicing of mitotic kinesins
Seemon Coomar, Alexander V. Penson, Juerg Schwaller, Omar Ibrahim Abdel-Wahab, Dennis G. Gillingham
The paper identifies two mitotic kinesins aberrantly spliced due to RBM39 degradation by ArSulfs, linking this splicing change to antiproliferative effects.
bioRxiv · Feb 1, 2021 · PreprintMolecular Biology