Author

Phil Grayson

Harvard UniversityORCID 0000-0002-3680-2238Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 1 Organism:non-human primate· 1

Frequent Co-Authors

Margaret F. DockeriD· 4 shared Colin J. GarrowayiD· 3 shared Jennifer D. JeffreyiD· 3 shared Jonathan Mark WilsoniD· 3 shared Ken M. JeffriesiD· 3 shared Michael J. LawrenceiD· 3 shared Michael Patrick WilkieiD· 3 shared Richard G. ManzoniD· 3 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersGenomics

Margaret F. DockerORCID

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4 papers

Recent·Most cited

Differences in the transcriptome response in the gills of sea lamprey acutely exposed to 3-trifluoromethyl-4-nitrophenol (TFM), niclosamide or a TFM:niclosamide mixture

Michael J. Lawrence, Phil Grayson, Jennifer D. Jeffrey, Margaret F. Docker, Colin J. Garroway, Jonathan Mark Wilson, Richard G. Manzon, Michael Patrick Wilkie, Ken M. Jeffries

This study examines transcriptomic responses of sea lamprey gills to TFM, niclosamide, and their mixture, identifying gene expression changes related to cell cycle, DNA damage, and immune function.

Comparative Biochemistry and Physiology Part D Genomics and Proteomics · Aug 17, 2023Peer-reviewedGenomics

Transcriptomic impacts and potential routes of detoxification in a lampricide-tolerant teleost exposed to TFM and niclosamide

Michael J. Lawrence, Phil Grayson, Jennifer D. Jeffrey, Margaret F. Docker, Colin J. Garroway, Jonathan Mark Wilson, Richard G. Manzon, Michael Patrick Wilkie, Ken M. Jeffries

This study investigates the transcriptomic responses of bluegill to niclosamide and a TFM:niclosamide mixture, identifying detoxification mechanisms and cellular processes involved in tolerance.

Comparative Biochemistry and Physiology Part D Genomics and Proteomics · Mar 28, 2023Peer-reviewedGenomics

Variation in the transcriptome response and detoxification gene diversity drives pesticide tolerance in fishes

Michael J. Lawrence, Phil Grayson, Jennifer D. Jeffrey, Margaret F. Docker, Colin J. Garroway, Jonathan Mark Wilson, Richard G. Manzon, Michael Patrick Wilkie, Ken M. Jeffries

The paper examines how gene expression variation and detoxification gene diversity contribute to differential pesticide tolerance between invasive sea lamprey and a native bluegill species.

Environmental Science & Technology · Aug 16, 2022Peer-reviewedGenomics

The germline-specific region of the sea lamprey genome plays a key role in spermatogenesis

Tamanna Yasmin, Phil Grayson, Margaret F. Docker, Sara Victoria Good

The paper identifies genes in the germline-specific region of the sea lamprey genome and shows their enrichment in testis expression and potential role in sex determination.

bioRxiv · Sep 24, 2021 · PreprintGenomics