A Requirement for K+ Ion Dehydration Governs Gating of the Shaker K+ Channel: Quantum Calculations Show Complex Interactions of Ions, Water, Protons, and Protein Side Chains
Alisher M. Kariev, Regina R. Monaco, Michael E. Green
The paper uses quantum calculations to propose that K+ ion dehydration and proton interactions govern Shaker K+ channel gating, with implications for mutant behavior and flicker noise.
bioRxiv · Jul 7, 2026 · PreprintBiophysics