Emerging Activity Patterns and Synaptogenesis in Dissociated Hippocampal Cultures
Jyothsna Suresh, Mark R. Saddler, Vytas P. Bindokas, Anita P. Bhansali, Lorenzo L. Pesce, Janice Wang, Jeremy D. Marks, Wim van Drongelen
This study develops an automated synapse quantification algorithm to analyze synaptogenesis in dissociated hippocampal cultures and finds increased synaptic density with maturation and a reduction in excitatory synapses during the third week.
bioRxiv · May 18, 2023 · PreprintNeuroscience