The mutational signatures of poor treatment outcomes on the drug-susceptible Mycobacterium tuberculosis genome
Yiwang Chen, Qi Jiang, Peierdun Mijiti, Howard Eugene Takiff, Qian Gao
The paper identifies bacterial genomic variants and a mutational signature associated with poor treatment outcomes in drug-susceptible tuberculosis, while showing host factors are more important in prediction models.
eLife · May 3, 2023Peer-reviewedGenomics