Author

Christopher E. Ramsden

National Institute on Alcohol Abuse and AlcoholismORCID 0000-0002-4058-7630Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

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Organism:human· 1 Assay:proteomics· 1

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Gregory S. KeyesiD· 1 shared Roy G. CutleriD· 1 shared Xiufeng LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperNeuroscience

Gregory S. KeyesORCID

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1 paper

Recent·Most cited

Lipid-protecting disulfide bridges are the missing molecular link between ApoE4 and sporadic Alzheimers disease in humans

Christopher E. Ramsden, Roy G. Cutler, Xiufeng Li, Gregory S. Keyes

This paper identifies lipid-protecting disulfide bridges as the molecular mechanism linking ApoE4 to sporadic Alzheimer's disease by showing that ApoE2 and ApoE3 form disulfide bridges that protect lipids from peroxidation, while ApoE4 cannot.

Prostaglandins Leukotrienes and Essential Fatty Acids · Apr 5, 2025Peer-reviewedNeuroscience