Javier Gamboa

Amphitrophic Listeria monocytogenes causes one-third of invasive listeriosis yet remains undetected by clonal complex-based risk classification

The paper shows that a major fraction of invasive Listeria monocytogenes is misclassified by conventional clonal complex-based risk assessment and demonstrates that amphitrophic lineages, which combine virulence and persistence traits, constitute 31% of clinical isolates.

Amphitrophic Listeria monocytogenes: multi-dimensional genomic profiling reveals a third ecological strategy that challenges the virulence-persistence trade-off paradigm

This paper develops a multi-dimensional genomic scoring system to evaluate virulence, persistence, clonal context, and resistance in L. monocytogenes, revealing a third ecological strategy that challenges the virulence-persistence trade-off.