The paper investigates the association between genomic copy number variants and chronic wound microbiome species, finding significant links and highlighting the role of structural genomic variation in shaping the microbiome.

medRxiv · Oct 15, 2026 · PreprintGenetic & Genomic Medicine

Functionally enriched human polymorphisms associate to species in the chronic wound microbiome

Rebecca A. Gabrilska, Khalid Omeir, Jacob S. Ancira, Clint Miller, Craig D. Tipton, Kendra P. Rumbaugh, Joseph Wolcott, Ashley Noe, Kumudu Subasinghe, Megan Rowe, Nicole Phillips, Caleb D. Phillips

This study identifies genetic loci associated with bacterial species in chronic wounds, revealing functional pathways and co-occurrence relationships that influence wound microbiome composition.

npj Biofilms and Microbiomes · Oct 9, 2025Peer-reviewedGenetic & Genomic Medicine

HERITABLE TISSUE-SPECIFIC GENE EXPRESSION ASSOCIATES WITH CHRONIC WOUND MICROBIAL SPECIES

Khalid Omeir, Jacob S. Ancira, Rebecca A. Gabrilska, Craig D. Tipton, Clint L. Miller, Ashley Noe, Kumudu Subasinghe, Megan Rowe, Nicole Phillips, Joseph Wolcott, Caleb D. Phillips

The paper investigates how genetic regulation of tissue expression influences chronic wound microbiome composition through a microbiome-transcriptome-wide association study.

Wound Repair and Regeneration · Jun 27, 2025Peer-reviewedGenetic & Genomic Medicine