Pranay Sinha

Serum nutritional-metabolic recovery during tuberculosis treatment across BMI-defined undernutrition strata: A longitudinal proteomic reanalysis

This study reanalyzes longitudinal serum proteomics data from tuberculosis patients to assess how nutritional-metabolic recovery during treatment varies by baseline BMI, finding no significant BMI-dependent trajectories but an overall increase in a 36-protein summary axis.

Distinct transcriptional remodeling of immune and metabolic pathways in severe undernutrition during latent tuberculosis infection does not consistently predict tuberculosis progression across independent cohorts

The paper examines transcriptional changes in severe undernutrition during latent TB infection and finds inconsistent associations with TB progression across cohorts.

Analysis of the Cross-Study Replicability of Tuberculosis Gene Signatures Using 49 Curated Transcriptomic Datasets

The paper curates 49 TB transcriptomic datasets into a resource to assess gene signature replicability and demonstrates improved diagnostic accuracy through ensembling.