Andrew D. Rutenberg

Measurements of damage and repair in aging mice and humans reveals that robustness and resilience decrease with age, operate over broad timescales, and are affected differently by interventions

The paper measures damage and repair rates in aging mice and humans, finding that robustness and resilience decline with age, with robustness having a greater impact on damage accumulation.

Generating synthetic aging trajectories with a weighted network model using cross-sectional data

This paper develops a weighted network model to generate synthetic aging trajectories from cross-sectional health data, showing good agreement with observed mortality and health characteristics.

Probing the network structure of health deficits in human aging

The paper models human aging as a stochastic network of health attributes and shows that network structure influences the recovery of observational health data.