Topological Links in Predicted Protein Complex Structures Reveal Limitations of AlphaFold
Yingnan Hou, Tengyu Xie, Liuqing He, Liang Tao, Jing Huang
The paper identifies topological links in AlphaFold-Multimer-predicted protein complexes and proposes a method to detect them, finding about 0.7% of structures contain such links.
Communications Biology · Oct 28, 2023Peer-reviewedBioinformatics