Accessing pore-blocker bound and alternative conductive conformations of TMEM16A using PIP2-assisted adaptive sampling
Tanadet Pipatpolkai, Ee Hou Yong
This study uses PIP2-assisted adaptive sampling to model conductive conformations of TMEM16A, revealing key structural features and validating pore blocker binding sites.
bioRxiv · Aug 5, 2026 · PreprintBiophysics