Author

Marine Gauthier

Institut national de recherche en sciences et technologies du numériqueORCID 0000-0002-4658-4051Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Boris P. HejblumiD· 2 shared Denis M. AgnieliD· 2 shared Rodolphe ThiébautiD· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBioinformatics

Boris P. HejblumORCID

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2 papers

Recent·Most cited

Distribution-free complex hypothesis testing for single-cell RNA-seq differential expression analysis

Marine Gauthier, Denis M. Agniel, Rodolphe Thiébaut, Boris P. Hejblum

This paper introduces a distribution-free method for scRNA-seq differential expression analysis that handles complex hypotheses and multiple conditions, showing good performance in simulations and a real dataset.

bioRxiv · May 21, 2021 · PreprintBioinformatics

dearseq: a variance component score test for RNA-Seq differential analysis that effectively controls the false discovery rate

Marine Gauthier, Denis M. Agniel, Rodolphe Thiébaut, Boris P. Hejblum

dearseq is a differential expression analysis method that controls the false discovery rate without assuming data distribution, showing improved performance over existing methods in simulations and real data.

NAR Genomics and Bioinformatics · Nov 19, 2020Peer-reviewedBioinformatics