Author

Leonardo Cotta

Vector InstituteORCID 0000-0002-4751-7643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Assay:protein sequence· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alán Aspuru‐GuzikiD· 1 shared Chris J. MaddisoniD· 1 shared Ella Miray RajaonsoniD· 1 shared Haonan DuaniD· 1 shared Marta SkretaiD· 1 shared Nikita Dhawan· 1 shared

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2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Alán Aspuru‐GuzikORCID

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1 paper

Recent·Most cited

Boosting the Predictive Power of Protein Representations with a Corpus of Text Annotations

Haonan Duan, Marta Skreta, Leonardo Cotta, Ella Miray Rajaonson, Nikita Dhawan, Alán Aspuru‐Guzik, Chris J. Maddison

This study shows that fine-tuning protein models on text annotations improves their predictive power for function prediction tasks, outperforming BLAST in some cases.

Nature Machine Intelligence · Aug 18, 2025Peer-reviewedBiochemistry