Author

James Guy Lyons

The University of SydneyORCID 0000-0002-4835-4663Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:simulation· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Ava DashtiiD· 1 shared Daniel AberdamiD· 1 shared David Martínez-MartíniD· 1 shared Dina JavidjamiD· 1 shared Huiqing ZhouiD· 1 shared Julian A. ArtsiD· 1 shared Mojdeh AbbasiiD· 1 shared Neda Khodabakhsh JonianiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Ava DashtiORCID

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2 papers

Recent·Most cited

Perturbation of epithelial and limbal stem cell identity in a mouse model of pathologic corneal neovascularization

Mojdeh Abbasi, Dina Javidjam, Julian A. Arts, Petros Moustardas, Ava Dashti, Daniel Aberdam, James Guy Lyons, Stephanie Louise Watson, Huiqing Zhou, Neil Lagali

This study examines the effects of corneal injury and duloxetine treatment on limbal stem cell identity using single-cell transcriptomics in a mouse model.

Communications Biology · Aug 6, 2026Peer-reviewedMolecular Biology

Intercellular forces driving stratification in a two-layer corneal epithelium: Insight from a Voronoi cell-based simulation model

Neda Khodabakhsh Joniani, David Martínez-Martín, Peter Kim, James Guy Lyons

This paper develops a Voronoi cell-based simulation model to study corneal epithelial stratification, revealing how cell delamination and mechanical forces drive tissue renewal and repair.

PLoS Computational Biology · Feb 20, 2026Peer-reviewedCell Biology