Failure to replicate the association of rare loss-of-function variants in type I IFN immunity genes with severe COVID-19
Gundula Povysil, Guillaume Butler‐Laporte, Ning Shang, Chen Wang, Atlas Khan, Manal A. Alaamery, Tomoko Nakanishi, Sirui Zhou, Vincenzo Forgetta, Robert J. M. Eveleigh, Mathieu Bourgey, Naveed Aziz, Steven J.M. Jones, Bartha Maria Knoppers, Stephen W. Scherer, , Krzysztof Kiryluk
The paper investigates the association of rare loss-of-function variants in type I IFN immunity genes with severe COVID-19 and finds no significant association.
Journal of Clinical Investigation · May 27, 2021Peer-reviewedGenetic & Genomic Medicine