Evaluating sequencing strategies for endometrial microbiome profiling in endometrial cancer: a comparative study of short- and long-read 16S rRNA approaches
Sophia Bebelman, Anastasiia Artuyants, Bianca Nijmeijer, Sandra J. Fitzgerald, Claire Henry, Cherie Blenkiron
This study compares short-read and long-read 16S rRNA sequencing for endometrial microbiome profiling in endometrial cancer, finding that long-read sequencing offers better species-level resolution but faces variability in low-yield samples.
Cancer Reports · Apr 1, 2026Peer-reviewedCancer Biology