Cell-type-specific alternative polyadenylation (APA) genes reveal the function of dynamic APA in complex tissues
Yulong Bai, Yidi Qin, Zhenjiang Fan, Robert M. Morrison, Kyong Nyon Nam, Hassane M. Zarour, Radosveta P. Koldamova, Quasar Saleem Padiath, Soyeon Kim, Hyun Jung Park
The paper introduces scMAPA, a tool to identify cell-type-specific APA genes in scRNA-Seq data, showing improved power and interpretability in human and mouse datasets.
bioRxiv · Jul 30, 2020 · PreprintBioinformatics