Author

Gowthami Somepalli

University of Maryland, College ParkORCID 0000-0002-5380-1413Unclaimed ORCID profile · follow to get notified of new preprints

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Systems Biology· 1

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

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Arashdeep SinghiD· 1 shared Sarthak SahooiD· 1 shared Sridhar S. HannenhalliiD· 1 shared

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2021-2021 · peak 1/yr

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Arashdeep SinghORCID

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Systems BiologyPLoS Computational BiologyPeer-reviewedJul 16, 2021

Prioritizing and characterizing functionally relevant genes across human tissues

Gowthami Somepalli, Sarthak Sahoo, Arashdeep Singh, Sridhar S. Hannenhalli

This paper introduces FUGUE, a machine learning model that predicts tissue-relevant genes across 30 human tissues using transcriptional and network features, outperforming conventional metrics and providing prioritized gene lists.

17 citations

humanbulk RNA-seq