Author

Johannes Nuebler

Massachusetts Institute of TechnologyORCID 0000-0002-5404-1604Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:Hi-C· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Benedikt Obermayer· 1 shared Guanjue XiangiD· 1 shared Jiahao YangiD· 1 shared Lin AniD· 1 shared Michael Wolff· 1 shared Qunhua LiiD· 1 shared Ross C. HardisoniD· 1 shared Tao YangiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Benedikt Obermayer

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2 papers

Recent·Most cited

Hierarchical Domain Structure Reveals the Divergence of Activity among TADs and Boundaries

Lin An, Tao Yang, Jiahao Yang, Johannes Nuebler, Guanjue Xiang, Ross C. Hardison, Qunhua Li, Yu Zhang

OnTAD identifies hierarchical TAD structures from Hi-C data with improved accuracy and speed, revealing new insights into TAD organization and gene regulation.

Genome biology · Dec 1, 2019Peer-reviewedBioinformatics

Emergence of robust nucleosome patterns from an interplay of positioning mechanisms

Johannes Nuebler, Michael Wolff, Benedikt Obermayer, Wolfram Möbius, Ulrich Gerland

The paper shows that nucleosome positioning patterns are robust across species and conditions due to statistical positioning emerging from complex mechanisms, with species-specific renormalization of nucleosome softness.

bioRxiv · Oct 1, 2018 · PreprintBiophysics