Kidney single-cell transcriptomes uncover SGLT2i-induced metabolic reprogramming via restoring glycolysis and fatty acid oxidation
The paper analyzes single-cell RNA sequencing data to show SGLT2 inhibition restores metabolic dysfunction in diabetic kidney disease by altering glycolysis and fatty acid oxidation in proximal tubule cells.
bioRxiv · Oct 31, 2023 · PreprintGenetics