Neural Potts Model
Tom Sercu, Robert Verkuil, Joshua Meier, Brandon Amos, Zeming Lin, Caroline Chen, Jason J. Liu, Yann LeCun, Alexander W. Rives
The paper introduces a Neural Potts Model that predicts pairwise coupling matrices for protein families using amortized optimization, showing improved performance on low-depth multiple sequence alignments.
bioRxiv · Apr 8, 2021 · PreprintBioinformatics