Exploring the limits of ComBat method for multi-site diffusion MRI harmonization
Suheyla Cetin Karayumak, Katharina Stegmayer, Sebastian Walther, Philip R. Szeszko, T. J. Crow, Anthony C. James, Matcheri S. Keshavan, Marek R. Kubicki, Yogesh Rathi A
The paper evaluates the ComBat method for multi-site diffusion MRI harmonization, finding that it preserves biological variability in some sites but not others and is sensitive to preprocessing differences.
bioRxiv · Nov 20, 2020 · PreprintNeuroscience