Impact of sequence variant detection and bacterial DNA extraction methods on the measurement of microbial community composition in human stool
Riley Hughes, Zeynep Alkan, Nancy L. Keim, Mary E. Kable
This paper compares DNA extraction kits and sequence analysis methods for microbial community profiling in human stool, finding DADA2 outperforms QIIME 1 and DNA stabilization reagents have a greater impact than extraction kits.
bioRxiv · Nov 1, 2017 · PreprintMolecular Biology