A Computational Approach for Structural and Functional Analyses of Disease-associated Mutations in the Human CYLD Gene
Arpita Singha Roy, Tasmiah Feroz, Md. Kobirul Islam, Md. Adnan Munim, Dilara Akhter Supti, Nusrat Jahan Antora, Hasan Al Reza, Supriya Gosh, Newaz Mohammed Bahadur, Mohammad Rahanur Alam, Md. Shahadat Hossain
The paper identifies deleterious nsSNPs in the CYLD gene using computational tools and highlights two significant mutations affecting CYLD-ubiquitin interaction and protein stability.
bioRxiv · Nov 16, 2023 · PreprintBioinformatics