Exploring G-quadruplex structure in PRCC-TFE3 fusion Oncogene: Plausible use as anti cancer therapy for translocation Renal cell carcinoma (tRCC)
The paper identifies G-quadruplex forming sequences in the PRCC-TFE3 fusion gene and demonstrates their stabilization by pyridostatin, suggesting potential as a therapeutic target for tRCC.
bioRxiv · Jul 6, 2023 · PreprintMolecular Biology