Sequence-based correction of barcode bias in massively parallel reporter assays
Dongwon Lee, Ashish Kapoor, Changhee Lee, Michael Mudgett, M Beer, Aravinda Chakravarti
This paper introduces a sequence-based method to correct barcode bias in MPRA experiments, improving detection of functional regulatory variants and capturing post-transcriptional regulatory features.
Genome Research · Sep 1, 2021Peer-reviewedBioinformatics